STANDARDIZATION OF Tl-201 RADIOACTIVE SOLUTION
نویسندگان
چکیده
The standardization of Tl, using the 4π(PC)-NaI(Tl) coincidence system, is presented. The disintegration rate was determined by the extrapolation technique, using two methods: electronic discrimination and external absorbers. A Monte Carlo simulation program, developed in our laboratory, which predicts the behavior of the extrapolation curve, was applied and the results were compared with experimental values.
منابع مشابه
Axonal transport of rubidium and thallium in the olfactory nerve of mice.
Following intranasal administration of radioactive (86)Rb(+) and (201)Tl(+) in mice, we observed this direct transport via the olfactory nerve pathway. The (86)RbCl and (201)TlCl solutions were administered to two groups of mice, the unilateral intranasal and intravenous administration groups. After sacrifice, their heads were divided into the right and left side, which were then subdivided int...
متن کاملStandardization and measurement of gamma-ray probability per decay of 177Lu.
The procedure followed by the Nuclear Metrology Laboratory (LMN), at the Nuclear and Energy Research Institute (IPEN), for the primary standardization of (177)Lu is described. This radionuclide is widely used in radiopharmacy due to its convenient half-life and emitted beta ray energies. The (177)Lu solution was supplied during an international comparison sponsored by BIPM in 2009 and the prima...
متن کاملLessons from the Tc-99m shortage: implications of substituting Tl-201 for Tc-99m single-photon emission computed tomography.
BACKGROUND In 2009, the Chalk River nuclear reactor closed for repairs that led to a critical shortage of technetium-99m (Tc-99m). Several centers used thallium-201 (Tl-201) as an alternative radiotracer for myocardial perfusion imaging. Because Tl-201 is considered by many as a suboptimal radiotracer, we sought to understand the impact of using Tl-201 (during the Tc-99m shortage) on downstream...
متن کاملA new method for crosstalk correction in simultaneous dual-isotope myocardial imaging with Tl-201 and I-123.
We have developed a new method of crosstalk correction in simultaneous dual-isotope imaging with Tl-201 and I-123 by using crosstalk ratios and a blurring filter. Single isotope myocardial studies (10 for Tl-201 and 7 for I-123) were performed with a dual energy window acquisition mode and two low energy general-purpose collimators. Then two planar images acquired with dual energy windows for a...
متن کاملBiological safety of nasal thallium-201 administration: a preclinical study for olfacto-scintigraphy.
Thallium-201/Nasal administration/Biological safety/Preclinical study. Nasal administration of thallium-201 (Tl) has previously been shown to be useful for the assessment of olfactory nerve connectivity in vivo. We assessed the biological effects of nasal Tl administration in mice to determine its safety before conducting clinical trials on humans. Tl uptake was evaluated in normal mice (n = 5)...
متن کامل